Are you struggling with stress, anxiety, or insomnia and searching for a natural, effective solution? Imagine a life where you can experience calmness, improved focus, and restful sleep without feeling drowsy or overwhelmed. You're in luck because there's a powerful, naturally occurring compound that can help you achieve just that. Say hello to L-theanine, your potential new ally in combating stress, anxiety, and sleepless nights.

L-theanine is a unique amino acid found primarily in tea leaves and some mushrooms. It has gained popularity in recent years due to its remarkable ability to promote relaxation without causing drowsiness. L-theanine works by increasing the levels of certain neurotransmitters in the brain, such as serotonin, dopamine, and GABA, which are responsible for regulating mood, sleep, and cognitive function. As a result, L-theanine can help alleviate stress, reduce anxiety, and support better sleep, all while maintaining alertness and mental clarity. With L-theanine, you can experience the calm and focus you need to thrive in your daily life, free from the burdens of stress, anxiety, and insomnia.

Here are the most commonly asked questions our pharmacists get about l-theanine:

Is it safe to take L-theanine every day?

For most people, taking L-theanine daily is considered safe, as it is a naturally occurring compound found in tea leaves and some mushrooms. However, it's always a good idea to consult with a healthcare professional before starting any new supplement regimen.

Which l-theanine product do you recommend?

Our top-recommended L-theanine products include:

1. L-Theanine 200mg by Integrative Therapeutics

2. L-Theanine 400mg by Pure Encapsulations

3. L-Theanine 200mg by Vital Nutrients

4. L-Theanine 100mg by Klaire Labs

5. L-Theanine 100mg by Douglas Laboratories

We also recommend several combination products containing L-theanine for stress reduction, anxiety management, and sleep support:

1. Cortisol Manager by Integrative Therapeutics: Cortisol Manager is a blend of L-theanine, ashwagandha, phosphatidylserine, magnolia, and epimedium, designed to support a healthy stress response by balancing cortisol levels. This formula can help reduce stress and promote relaxation, making it an excellent choice for individuals seeking a natural solution for stress management.

2. Pro-Som by Integrative Therapeutics: Pro-Som combines L-theanine with melatonin, magnolia bark, and 5-HTP to support restful sleep without causing morning grogginess. This formula is designed to help individuals with insomnia or difficulty falling or staying asleep, promoting a more restorative night's sleep.

3. Insomnitol by Designs for Health: Insomnitol is a comprehensive sleep support formula that includes L-theanine, melatonin, valerian root, passionflower, chamomile, lemon balm, and 5-HTP. This blend of ingredients works together to promote relaxation, ease anxiety, and support a healthy sleep cycle, making it ideal for individuals who struggle with sleep issues.

4. NeuroCalm by Designs for Health: NeuroCalm is a blend of L-theanine, GABA, 5-HTP, inositol, taurine, and several B vitamins. This formula is designed to support a balanced mood, reduce stress, and promote relaxation without causing drowsiness. It's ideal for individuals who experience anxiety or stress-related mood imbalances.

5. Cortisol Calm by Pure Encapsulations: Cortisol Calm combines L-theanine with rhodiola, ashwagandha, magnolia, and B vitamins to support healthy cortisol levels and stress resilience. This supplement can help promote relaxation, reduce stress, and support overall well-being, making it suitable for those who need stress management support.

6. Best-Rest Formula by Pure Encapsulations: Best-Rest Formula is a blend of L-theanine, melatonin, valerian root, passionflower, chamomile, lemon balm, and GABA, designed to promote restful sleep and relaxation. This comprehensive formula is ideal for individuals seeking a natural solution for sleep support and improved sleep quality.

Each of these combination products offers unique benefits for managing stress, anxiety, or sleep issues, depending on the specific ingredients and their synergistic effects. It's essential to consult with a healthcare professional before starting any new supplement regimen, as they can help you determine which product is best suited for your individual needs and goals.

Which dose of l-theanine should I take? What is the best dose to start with?

Determining the appropriate dose of L-theanine can vary depending on individual needs and desired outcomes. A common starting point is typically between 100-200 mg per day, as this range has been shown to provide relaxation and anxiety-reducing benefits without causing drowsiness. However, some people may require higher doses up to 400 mg per day for more pronounced effects. It's always best to start with a lower dose and gradually increase as needed, while closely monitoring your body's response. Consulting with a healthcare professional, such as a clinical pharmacist or integrative medicine practitioner, can help guide you in determining the optimal L-theanine dosage for your specific situation and goals. Remember that individual responses may vary, so it's essential to find the dose that works best for you.

What are the negative side effects of L-theanine?

L-theanine is generally well-tolerated, with few reported side effects. Some individuals may experience mild side effects such as headache, dizziness, or upset stomach. If you experience any adverse effects, consult your healthcare provider.

How good is L-theanine for anxiety?

L-theanine has been found to promote relaxation and help reduce anxiety by increasing levels of certain neurotransmitters in the brain, such as GABA, dopamine, and serotonin. Many people find L-theanine beneficial for managing anxiety symptoms without causing drowsiness.

Is it safe to take L-theanine every night?

Yes, L-theanine is safe to take every night for most individuals, as it can help improve sleep quality without causing dependence or next-day drowsiness. However, it's essential to consult with a healthcare provider before starting a new supplement routine.

Should I take L-theanine at night or morning?

The best time to take L-theanine depends on your personal needs and preferences. If you're using it to reduce anxiety or enhance focus, taking it in the morning or early afternoon may be beneficial. If you're using it for sleep support, taking it in the evening or before bedtime is recommended.

Who should not take theanine?

Although L-theanine is generally safe, individuals with a known allergy to L-theanine or those taking certain medications, such as blood pressure medications, should consult with their healthcare provider before using L-theanine.

Does L-theanine affect kidneys?

There is limited research on the direct impact of L-theanine on kidney function. However, no significant adverse effects on the kidneys have been reported. If you have concerns about kidney health or are taking medications that impact kidney function, consult with your healthcare provider before using L-theanine.

What are the long-term effects of L-theanine?

Long-term effects of L-theanine are not well-studied, but short-term use appears to be safe for most individuals. If you're considering long-term use, it's important to discuss your plans with a healthcare professional.

Can L-theanine cause weight gain?

There is no evidence to suggest that L-theanine directly causes weight gain. In fact, it may help reduce stress and anxiety, which can contribute to healthier eating habits and weight management.

What to avoid when taking L-theanine?

When taking L-theanine, it's essential to follow the recommended dosage and consult with a healthcare professional if you're taking other medications or supplements, as interactions may occur. It's also important to avoid consuming excessive amounts of caffeine, as L-theanine may amplify the stimulant effects of caffeine, potentially causing jitteriness or increased heart rate.

Is L-theanine hard on the liver?

There is no evidence to suggest that L-theanine has adverse effects on liver function. However, if you have liver concerns or are taking medications that impact liver function, consult with your healthcare provider before using L-theanine.

Is melatonin or L-theanine better?

Melatonin and L-theanine serve different purposes, and the choice between them depends on individual needs. Melatonin is a hormone that helps regulate sleep-wake cycles and is often used for jet lag or sleep disorders. L-theanine promotes relaxation without drowsiness and can be helpful for managing anxiety and sleep issues. Consult with a healthcare professional to determine which supplement is best for you.

Does L-theanine give you energy?

L-theanine doesn't directly provide energy but can promote alert relaxation, which may improve focus and mental clarity without causing drowsiness or overstimulation.

How much caffeine is in L-theanine?

L-theanine does not contain caffeine. It is an amino acid that naturally occurs in tea leaves alongside caffeine but has distinct effects on the brain.

Can L-theanine cause brain fog?

L-theanine is not typically associated with causing brain fog. In fact, it may help improve mental clarity and focus by promoting a state of relaxed alertness.

How often can you take L-theanine for anxiety?

L-theanine can be taken daily for anxiety management. However, the ideal dosage and frequency depend on individual needs and should be determined in consultation with a healthcare professional.

What foods are high in L-theanine?

L-theanine is most commonly found in tea leaves, particularly green and black tea varieties. Some types of mushrooms, such as Bay Bolete, also contain trace amounts of L-theanine.

What foods are rich in L-theanine?

As mentioned earlier, tea leaves (green and black tea) and some mushrooms, like Bay Bolete, are the primary natural sources of L-theanine.

Can I take L-theanine and magnesium together?

L-theanine and magnesium can generally be taken together, as both supplements have complementary benefits in promoting relaxation, reducing anxiety, and supporting sleep. However, always consult with a healthcare professional before combining supplements.

Can you take vitamin D and L-theanine together?

There are no known interactions between vitamin D and L-theanine, making it generally safe to take both supplements together. However, it's essential to consult with a healthcare professional before starting any new supplement regimen.

Can theanine make anxiety worse?

While L-theanine typically helps reduce anxiety, individual responses may vary. If you find that L-theanine exacerbates your anxiety, discontinue use and consult your healthcare provider.

Benefits of taking l-theanine
Key Benefits of L-Theanine

Emily's 30-day journey on L-theanine. Here's what happened...

Emily, a 34-year-old graphic designer had been struggling with stress, anxiety, and occasional sleepless nights. Like many others, she searched for a natural solution to help her find some peace and focus in her daily life. Our pharmacist recommended L-theanine and she decided to give it a try. She graciously shared her personal journey with us for this article. Here is Emily's experience:
First day:
Emily took her first dose of L-theanine (200 mg) in the morning with her breakfast. Within an hour, she noticed a subtle sense of calmness and mental clarity without feeling drowsy. She felt more focused and less anxious as she went about her day. The effects wore off by the evening.
End of the first week:
By the end of the first week, Emily had been consistently taking L-theanine daily. She experienced a significant improvement in her overall stress levels and found it easier to concentrate at work. The racing thoughts that once plagued her before bedtime had subsided, and she was able to fall asleep more quickly.
End of the second week:
Emily continued to enjoy the benefits of L-theanine, but on day 11, she forgot to take her supplement. That day, she noticed that her anxiety levels were slightly higher, and her focus was not as sharp. This made her realize the positive impact L-theanine had on her well-being. She resumed taking L-theanine the next day and noticed the difference in her mood and focus.
End of the third week:
At this point, Emily had established a routine with her L-theanine supplement and was feeling more in control of her stress and anxiety. She also observed that her sleep quality had improved, and she was waking up feeling more refreshed and energized.
End of the fourth week:
By the end of the 30-day experiment, Emily was genuinely impressed with the benefits she experienced from taking L-theanine. Her stress and anxiety levels were significantly lower, and she enjoyed better sleep and improved focus throughout the day. She did have a couple more days when she forgot to take her supplement, and she noticed a difference in her mood when she missed more than 2 consecutive days.
Emily's journey with L-theanine highlights the effectiveness of this natural supplement in managing stress, anxiety, and sleep issues. While her experience may not be the same for everyone, it offers an authentic account of how L-theanine can provide mental clarity and focus without causing drowsiness. It's essential to remember that consistency is vital in achieving the best results, as Emily learned from the days she missed her L-theanine dose.
If you're considering trying L-theanine for similar concerns, it's always a good idea to consult with a healthcare professional to discuss your individual needs and determine the appropriate dosage for you. Emily's experience with L-theanine serves as an encouraging example of how this natural supplement can help improve mental well-being and overall quality of life.


L-theanine is a remarkable amino acid with numerous potential benefits for relaxation, anxiety relief, and sleep support. By understanding its properties and incorporating high-quality L-theanine supplements into your wellness routine, you can experience these benefits for yourself.

Our online supplement store at offers a selection of professional-grade L-theanine products, with a 12% discount for our valued Drug Mart Pharmacy customers. And for more helpful information on health and wellness, be sure to explore the other articles on our Drug Mart Pharmacy blog, such as our guide to the power of comprehensive care or tips for better sleep.

Our clinical pharmacists at Drug Mart Pharmacy, with backgrounds in integrative and functional medicine, are available to answer your questions and guide you towards the best L-theanine products for your individual needs. By incorporating L-theanine into your wellness routine and following professional guidance, you can unlock its potential benefits for relaxation, anxiety relief, and better sleep. Happy relaxation!